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KMID : 0358320070480010082
Korean Journal of Urology
2007 Volume.48 No. 1 p.82 ~ p.86
Experience of Subureteral Polydimethylsiloxane Injection Treatment in Children with Vesicoureteral Reflux
Sung Hyun-Hwan

Park Heung-Jae
Park Kwan-Hyun
Abstract
Purpose: Our data was retrospectively reviewed to assess the efficacy, safety and costs of endoscopic subureteral polydimethylsiloxane(PDS, Macroplastique¨Þ) injection treatment for children with vesicoureteral reflux(VUR).

Materials & Methods: etween December 1997 and May 2006, a total of 24(29 renal units) VUR patients, whose parents showed reluctance toward open surgery, underwent subureteral PDS injection treatment. All of the patients were postoperatively assessed by voiding cystourethrography(VCUG) and ultrasound to evaluate any complications and reflux. The medical costs of the injection treatment were compared with those of open surgery for VUR over the same period.

Results: The mean follow-up was 15 months(range 2-72). Of the 29 renal units treated, 24(82.8%) were cured. Hydronephrosis, which postoperatively developed in three renal units, was spontaneously improved or resolved after minimal endourological procedures. Temporary gross hematuria and voiding difficulty occurred in one patient each, but were also improved. The total medical costs of the injection treatment were cheaper than those of open surgery(p£¼0.05).

Conclusion: An endoscopic subureteral PDS injection is an effective and safe procedure; in addition, compared to open surgery, is an economic treatment for children with VUR.(Korean J Urol 2007;48:82-86)
KEYWORD
Vesicoureteral reflux, Injection, Treatment, Polydimethylsiloxane, Child
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